Good question.
The physical symptoms are almost identical - intrusive thoughts, mood swings based on whether they text back, that chest feeling. Research on limerence shows it activates the same brain regions as addiction, which is why it feels so compulsive.
The difference with your twin is the reciprocity. Not the runner-chaser thing (which gets misused to justify one-sided situations), but actual mutual recognition. If you met them and they felt nothing while you felt everything, that’s a pretty clear sign. Twin flames should have both people experiencing the intensity, even if one runs from it initially.
That’s not to say that just because you go through separation that makes it limerance either. This is where the external signs, like telepathy or something, can really come into play.
Limerence makes you need them to feel whole - you’re constantly checking for validation, analyzing every interaction, feeling high when they respond and devastated when they don’t. The real work, whether this is a twin flame or not, is getting to where you feel whole without them. If you can’t imagine being okay without them in your life, that’s the wound talking, not spiritual connection.
Sometimes we get so caught up in the intensity that we forget to ask whether this is actually helping us grow or just keeping us stuck.